Shigellosis is one of the most important causes of morbidity and mortality from gastrointestinal infection in the world. There are an estimated 125 million cases and >100,000 deaths caused by shigellosis annually. There is currently no vaccine for shigellosis. SIGHTM is committed to quantifying the extent of the problem, establishing the current state of the art for shigellosis vaccine development and promoting development and implementation of a vaccine against shigellosis.